Sabapathy K., Balzer L., Larmarange Joseph, Block L., Floyd S., Iwuji C., Wirth K., Ayles H., Fidler S., Kamya M., Petersen M., Havlir D., Dabis F., Moore J. et Hayes R. (2022) « Achieving the UNAIDS 90–90-90 targets: a comparative analysis of four large community randomised trials delivering universal testing and treatment to reduce HIV transmission in sub-Saharan Africa », BMC Public Health, 22 (1) (décembre 13), p. 2333. DOI : 10.1186/s12889-022-14713-5. https://doi.org/10.1186/s12889-022-14713-5.
Résumé : Four large community-randomized trials examining universal testing and treatment (UTT) to reduce HIV transmission were conducted between 2012–2018 in Botswana, Kenya, Uganda, Zambia and South Africa. In 2014, the UNAIDS 90–90-90 targets were adopted as a useful metric to monitor coverage. We systematically review the approaches used by the trials to measure intervention delivery, and estimate coverage against the 90–90-90 targets. We aim to provide in-depth understanding of the background contexts and complexities that affect estimation of population-level coverage related to the 90–90-90 targets.
Mots-clés : Antiretroviral treatment, HIV, Treatment as Prevention, UNAIDS 90-90-90, Universal Testing and Treatment.