LU6KPRMH
type: UserItem
resource: Perspectives of injectable long acting antiretroviral therapies for HIV treatment or prevention: understanding potential users’ ambivalences
access date: 2020-05-13 13:55:20
repository: Crossref

Perspectives of injectable long acting antiretroviral therapies for HIV treatment or prevention: understanding potential users’ ambivalences
type: AcademicArticle
abstract: Recent clinical trial data showed that injectable long-acting antiretroviral treatment (LA-ART) every four or eight weeks could become an alternative option for HIV treatment or prevention. The purpose of our study was to explore perceptions and potential users' points of views of this new mode of administration through individuals' therapeutic itinerary and their singular history with ART. Between 2018 and 2019, a qualitative study was conducted in two University Hospitals in Paris, France. In-depth interviews were conducted with 15 virologically controlled People Living with HIV (PLWH) and 13 men on pre-exposure prophylaxis (PrEP) for at least six months. Interviews, focused on the daily experience with ART, were recorded, transcribed, and analyzed using thematic content analysis. Collected discourses were organized around three emergent concerns: social, material and experimental. Each of these concerns was perceived as ambivalent, balanced by skepticism and hope. It revealed the complexity of each individual's relationship to their HIV treatment or PrEP, leading to balance the injectable LA-ART popularity reported within clinical trials. This new mode of administration may be a suitable alternative for some PLWH and PrEP users, a "simplification" compared to the oral route. It opens a window for "customizable" ART-treatment according to individuals' lives. Injectable ; long-acting antiretroviral therapies ; acceptability ; PrEP ; antiretroviral treatment ; qualitative study
pages: 155-161
doi: 10.1080/09540121.2020.1742869
citation key: carillonPerspectivesInjectableLong2020
short title: Perspectives of injectable long acting antiretroviral therapies for HIV treatment or prevention
language: en
extra: https://www.documentation.ird.fr/hor/fdi:010078928 WOS:000526796400020
creator: Person
author list: Person
is part of: Issue
  date: 2020-03-19
  volume: 32
  issue: sup2
  is part of: AIDS Care
    type: Journal
    issn: 0954-0121, 1360-0451

Person
given name: Séverine
surname: Carillon

Person
given name: Lucille
surname: Gallardo

Person
given name: Françoise
surname: Linard

Person
given name: Catherine
surname: Chakvetadze

Person
given name: Jean-Paul
surname: Viard

Person
given name: Agnès
surname: Cros

Person
given name: Jean-Michel
surname: Molina

Person
given name: Laurence
surname: Slama